Copner Biotech have developed bespoke 3D modelling and printing techniques in order to create 3D PETG cell culture scaffold structures. These scaffolds are housed in a 24 well plate and shipped non-sterile.

3D Scaffold Benefits

• Cells exhibit more physiologically relevant morphologies when compared to 2D culture
• Physiologically relevant environment and more healthy biomarkers
• Enhanced cell capture and adhesion whilst using low cell seeding concentrations
• Uses up to 10 times less antibody for staining applications
• Encourages the growth of balanced and confluent cell systems
• Reproducibility due to lack of batch to batch variation
• Easy to use and has a 24 month shelf life

Scaffold Structure

• Discrete oxygen and nutrient gradients across the scaffold interface, due to heterogeneity in pore size and distribution. This encourages cell proliferation and migration.
• The PETG material has been altered to optimise surface roughness and improve cell attachment and proliferation.
• The 3D PETG scaffold system has interconnected pores throughout the entire structure and is designed to easily culture and harvest spheroid cultures.
• Scaffolds show rigidity and do not degrade – perfect for long term culture of cells!

Applications

• Cells demonstrate successful migration from the centre to the periphery of the scaffold, resulting in a balanced, confluent cell system that resembles the patterns of in vivo tissue.
• Cellular proliferation – the PETG material mediates cell division events, whilst minimising cell loss, resulting in significant expansion of cultures over a short space of time.
• Cellular attachment and viability
• Spheroid formation – scaffolds encourage the formation of spheroid cultures
• Can be used with induced pluripotent stem cells (iPSCs)
• For more details, download our poster and brochure from the ‘Downloadable Documents’ section!

Check out the video below for more information…

Still have a question?

Email Atqiya, our Product Executive, here!